Gene regulation by RNA interference
miRNA mimics & inhibitors
We provide chemically synthesized RNA oligonucleotides optimized to mimic or inhibit miRNA molecules.
Custom synthesized miRNA mimics and inhibitors are available with different labels and can be linked to cholesterol to increase cellular uptake. Other modifications are available on request, like covalently-bond peptides, modified bases, dyes and more.
What are miRNAs ?
miRNAs (for microRNAs) are small non-coding RNAs forming short hairpins.
They are involved in gene expression regulation and RNA silencing mostly by inducing the active degradation of the targeted mRNA or by preventing its translation.