Immunology and Infectious Disease
Peptides that stimulate adaptive and innate immunity
Host defense peptides can perform a wide range of activities including microbial interactions, chemotaxis, stimulation of chemokines, endotoxin clearance, anti-inflammatory activities etc.
Most popular are the Antimicrobial Peptides that serve as important components of the innate defense system.
Other peptide classes include those that bind to MHC to elicit immune response (such as OVA), proinflammatory and immunoregulatory functional peptides (such as complement protein components, C3, C5 etc.), specific viral envelop processed peptides (HIV, HCV etc.), animal derived anti-microbial peptides (such as magainins), and peptides that can alter the biofilms make up (such as Tet 20, NRC etc.).