Peptides

CSP-1, Competence-Stimulating Peptide-1 - 1 mg

134.00
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  • Cat.Number : AS-63779
  • Availability :
    In stock

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Competence stimulating peptide-1 is a 17 amino acids pheromone that is secreted by Streptococcus pneumoniae. CSP pheromone is used in-vivo for intercellular communication. This peptide activates signal transduction pathway ComABCDE, which regulates natural genetic transformation. The pheromone is ribosomally synthesized as precursor peptide. The mature pheromone is strain specific. CSP pheromone is produced by S. pneumoniae strain Rx, which is closely related to strain R6.

Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.

Specifications

Chemistry
Sequence one letter code
  • EMRLSKFFRDFILQRKK
Sequence three letter code
  • H-Glu-Met-Arg-Leu-Ser-Lys-Phe-Phe-Arg-Asp-Phe-Ile-Leu-Gln-Arg-Lys-Lys-OH
Molecular Formula
  • C103H168N30O24S1
Molecular Mass/ Weight
  • 2242.8
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • streptococcus
Codes
Code Nacres
  • NA.26

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