Preclinical CRO Services
Animal and analytical
GLP Services
Access comprehensive preclinical CRO services to ensure the safety of your novel therapeutic agents before clinical trials. Our offerings include in vivo and in vitro studies such as toxicology, pharmacokinetics, biodistribution, bioanalysis, and histopathology.
Our expert team is committed to delivering high-quality, GLP-compliant data to support your drug development process.
Toxicology Services
GLP preclinical toxicology studies assess the safety and potential toxicity of drug candidates before clinical trials. We provide in vitro and in vivo toxicology studies in rodent and larger animal models.
in vitro tox studies
- Cytotoxicity, Genotoxicity, Nephrotoxicity, and Hepatotoxicity
- Single-dose toxicity
- Toxicokinetics
in vivo tox studies
- Single-dose and repeated-dose toxicity
- Acute, sub-chronic, and chronic toxicity
- Tolerance and sensitization testing
- Toxicokinetics
Disease Models
We provide well-characterized, GLP-compliant disease models for in vivo and in vitro testing of potential treatments, specializing in neurology, immune-oncology, cardiometabolic, and rare genetic diseases. Our models enable precise evaluation of drug efficacy and safety, supporting the development of targeted therapies.
Examples of our expertise:
- Neurology: Neurodegenerative diseases, psychiatric conditions, aging models.
- Immuno-oncology: Humanized IC & IS models, inflammation models (psoriasis, DTH, NLRP3 inflammasome), comprehensive immuno-oncology readouts.
- Rare Genetic Diseases: Polycystic kidney disease, Stxbp1 epileptic encephalopathy, fragile X syndrome, ALS, Duchenne muscular dystrophy, vanishing white matter.
- Cardiometabolic: Ischemic heart disease, hypertrophic heart disease, type I & II diabetes, liver inflammation & fibrosis, NASH/NAFLD.
We also offer a diverse panel of rodent cancer cell line models to support oncology research. These models cover a range of cancer types, including breast, colorectal, skin, pancreas, lung, kidney, hematological, brain, bladder, and liver cancers.
Study adaptation
We offer flexible study designs tailored to meet your specific needs. Our expertise includes specialty designs such as microsurgery, immunotherapy studies in humanized animal models, development and evaluation of disease models, coagulation studies, stem cell therapy, vaccine efficacy and safety assessments, and pharmacokinetics of biologicals. Our adaptive approach ensures that our studies align with your project goals and regulatory requirements.
Regulatory Documentation and IND Filing Support
We provide comprehensive support in documenting preclinical study results to facilitate your IND application. Our team assists in the preparation of regulatory submissions by compiling essential data from preclinical studies, manufacturing processes, and other necessary regulatory documents. With our expertise, we help streamline the IND filing process, ensuring all documentation meets regulatory standards and supports your path to clinical trials.
Regulatory Compliance
We are committed to maintaining the highest standards of regulatory compliance in all our preclinical activities. Our operations are ISO 9001 certified and comply with GLP guidelines. We are also AAALAC accredited for rodent studies, reflecting our dedication to responsible animal care and use in research.
