Publications

Citation

Synthesis and biological evaluation of novel N,N′-bis-methylenedioxybenzyl-alkylenediamines as bivalent anti-Alzheimer disease ligands.

J Enzyme Inhibition Med Chem . 2014 Jan 09 ; 26(5) 706 | DOI : 10.3109/14756366.2010.548329.

• W. Luo
• et al

Products : Beta-Amyloid (1-42), sodium salt — AS-60883 ; Beta-Amyloid (1-42), sodium salt — AS-60883-01

Citation

A novel β-sheet breaker, RS-0406, reverses amyloid β-induced cytotoxicity and impairment of long-term potentiation in vitro.

Br J Pharmacol . 2002 Oct 16 ; 137(5) 676 | DOI : 10.1038/sj.bjp.0704911.

• Y. Nakagami
• et al

Products : Beta-Amyloid (1-42) Peptide HCl salt — AS-21793 ; Beta-Amyloid (1-42), sodium salt — AS-60883 ; Beta-Amyloid (1-42), sodium salt — AS-60883-01 ; Beta-Amyloid (1-42) Peptide HCl salt — AS-21791

Citation

6-Ethyl-N,N'-bis(3-hydroxyphenyl)[1,3,5]triazine-2,4-diamine (RS-0466) enhances the protective effect of brain-derived neurotrophic factor on amyloid beta-induced cytotoxicity in cortical neurones.

Pharmacol Toxicol . 2003 Dec 01 ; 93(6) 264 | DOI : 10.1111/j.1600-0773.2003.pto930603.x.

• T. Kubo
• et al

Products : Beta-Amyloid (1-42) Peptide HCl salt — AS-21793 ; Beta-Amyloid (1-42) Peptide HCl salt — AS-21791

Citation

A novel neurotrophic agent, T-817MA [1-{3-[2-(1-Benzothiophen-5-yl) Ethoxy] Propyl}-3-azetidinol Maleate], attenuates amyloid-β-induced neurotoxicity and promotes neurite outgrowth in rat cultured central nervous system neurons.

JPET . 2005 Mar 29 ; 314(1) 252 | DOI : 10.1124/jpet.105.083543.

• K. Hirata
• et al

Products : Beta-Amyloid (1-42) Peptide HCl salt — AS-21793 ; Beta-Amyloid (1-42) Peptide HCl salt — AS-21791

Citation

Ovariectomy combined with amyloid beta(1-42) impairs memory by decreasing acetylcholine release and alpha 7nAChR expression without induction of apoptosis in the hippocampus CA1 neurons of rats.

Neurotox Res . 2004 Jan 01 ; 6(4) 299 | DOI : 10.1007/bf03033440

• K. Iwasaki
• et al

Products : Beta-Amyloid (1-42) Peptide HCl salt — AS-21793 ; Beta-Amyloid (1-42) Peptide HCl salt — AS-21791

Citation

Cerebral ischemia combined with β-amyloid impairs spatial memory in the eight-arm radial maze task in rats.

Brain Res . 2006 May 26 ; 1097(1) 216 | DOI : 10.1016/j.brainres.2006.04.073.

• K. Iwasaki
• et al

Products : Beta-Amyloid (1-42) Peptide HCl salt — AS-21793 ; Beta-Amyloid (1-42) Peptide HCl salt — AS-21791

Citation

Nilvadipine prevents the impairment of spatial memory induced by cerebral ischemia combined with β-amyloid in rats.

Biol Pharm Bull . 2007 Apr 01 ; 30(4) 698 | DOI : 10.1248/bpb.30.698

• K. Iwasaki
• et al

Products : Beta-Amyloid (1-42) Peptide HCl salt — AS-21793 ; Beta-Amyloid (1-42) Peptide HCl salt — AS-21791

Reference

Structure of substrate-free human Insulin-degrading Enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE.

J Biol Chem . 2007 Jul 05 ; 282(35) 25453 | DOI : 10.1074/jbc.M701590200.

• H. Im
• et al

Products : Beta-Amyloid (1-40)-Lys(LC-biotin)-NH2, FAM-labeled - 0.1 mg — AS-61962-01

Citation

Monitoring the earliest amyloid-beta oligomers via quantized photobleaching of dye-labeled peptides.

Anal Biochem . 2008 Jul 19 ; 382(1) 29 | DOI : 10.1016/j.ab.2008.07.011.

• KD. Dukes

Products : Beta-Amyloid (1-40)-Lys(LC-biotin)-NH2, FAM-labeled - 0.1 mg — AS-61962-01

Citation

Protective role of Cys-178 against the inactivation and oligomerization of human insulin-degrading enzyme by oxidation and nitrosylation.

J Biol Chem . 2009 Oct 06 ; 284(49) 34005 | DOI : 10.1074/jbc.M109.030627.

• LA. Ralat
• et al

Products : Beta-Amyloid (1-40)-Lys(LC-biotin)-NH2, FAM-labeled - 0.1 mg — AS-61962-01