[Trp63, 64]-C3a (63-77) - 1 mg
- Cat.Number : AS-61119
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This peptide, which is a C-terminal analogue of the complement factor C3a, acts as an agonist to the C3a receptor. It is derived from the fifteen C-terminal residues (6-77) of C3a. In in vitro studies, both C 3a and this peptide have been shown to selectively bind to C3aRs and induce degranulation of C3aR-transfeted RBL-2H3 cells. There was also a rapid, transient and concentration-dependent hypertensive response observed in rats when infused intravenously with C3a and this peptide.
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Citations
Parallel detection of intrinsic fluorescence from peptides and proteins for quantification during mass spectrometric analysis
Anal Chem . 2011 Mar 15 ; 83(6) 2187 | DOI : 10.1021/ac103023q
- J. Russell
- et al