Tat-GluR23Y - 1 mg
- Cat.Number : AS-64429
- Manufacturer Ref. :
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The synthetic peptide (Tat-Glur23Y) contains tyrosine residues that blocks phosphorylation of alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor endocytosis. Previous research shows that Tat-Glur23Y blocks regulated AMPA and thereby prevents long-term depression (LTD) in structures such as the nucleus accumbens and dorsal hippocampus.
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Citations
Inhibiting PKMζ reveals dorsal lateral and dorsal medial striatum store the different memories needed to support adaptive behavior.
Learn. Mem . 2012 Jan 01 ; 19 307 | DOI : 10.1101/lm.025148.111
- WM. Pauli
- et al
Inhibition of PKMζ in nucleus accumbens core abolishes long-term drug reward memory
J Neurosci. . 2011 Apr 06 ; 31(14) 5436 | DOI : 10.1523/JNEUROSCI.5884-10.2011
- Y. Li
- et al