Oligos

Spacer C12 - 1 modification

42.60
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  • Cat.Number : MD-SP012-IN004
  • Availability :
    In production

Synthesis scale

Alternative choices

Spacer phosphoramidites are used during oligonucleotide synthesis to introduce a spacer arm into the sequence. Multiple additions of the different spacer molecules allow the precise length of the spacer arm to be controlled.

Several spacer modifications are available. Spacers C3, C8 (octanediol), 9, C12, HEG (hexaethylene glycol) and 18 can be used to bridge sections of oligos where no appropriate binding is possible.
The 3’ spacer-C3-CPG is used to introduce a terminal spacer which acts as a blocker of exonuclease and polymerase activity at the 3’ end.
Spacer-C18 can be used to add a very hydrophobic section to an oligonucleotide.
The dSpacer is used to create a stable abasic site within an oligonucleotide.

Specifications

Chemistry
Molecular Mass/ Weight
  • 264,31
Modification
Modification Position
  • 5'
  • IN
Storage & stability
Resuspension condition
  • - Spin the tube briefly to collect the pellet in the bottom of the tube - Add an appropriate volume of recommended buffer (refer to technical data sheet) - Allow the tube to stand a few minutes - Vortex the tube for 15 seconds
Storage Conditions
  • Dried Oligonucleotides are stable for 18 months at ambiant temperature. Oligonucleotides in solutions are stable for 24 months at -20°C. (Tolerance -20°C± 5°C. ) For more information please refer to the Reconstitution-Storage-Stability page
Activity
Usage
  • Research use
Codes
Code Nacres
  • NA.51

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