SensoLyte® AFC Caspase Profiling Kit Fluorimetric - 1 kit
- Cat.Number : AS-71116
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Caspases play important roles in apoptosis and cell signaling. They are also identified as drug-screening targets. AFC-based substrates yield blue fluorescence upon protease cleavage. They are widely used to monitor caspase activity.
The SensoLyte® Caspase Profiling Kit contains a series of AFC-based peptide substrates (Ex/Em=380 nm/500 nm) as fluorogenic indicators for assaying caspase protease activities. The kit contains a well-designed plate in which a series of AFC-based caspase substrates are coated with both positive and negative controls. It provides the best solution for profiling caspases or caspase inhibitors.
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Citations
Regulation of apoptosis and innate immune stimuli in inflammation-induced preterm labor.
J Immunol . 2013 Oct 25 ; 191(11) 5702 | DOI : 10.4049/jimmunol.1301604
- M.K. Jaiswal
- et al
Endoplasmic reticulum stress induces a caspase-dependent N-terminal cleavage of RBX1 protein in B cells.
J Biol Chem . 2012 Jul 20 ; 387(37) 31223 | DOI : 10.1074/jbc.M111.314583
- S. Shteingart
- et al
Zip6-attenuation promotes epithelial-to-mesenchymal transition in ductal breast tumor (T47D) cells.
Exp Cell Res . 2009 Oct 21 ; 316(3) 366 | DOI : 10.1016/j.yexcr.2009.10.011
- V. Lopez
- et al