[Lys(Me1)4]-Histone H3 (1-21) - 1 mg
- Cat.Number : AS-64459
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This is a monomethylated lysine at position 4 of the 1-21 amino acid histone H3 peptide. This form of histone methylation is characterized as being enriched around transcription start sites. It’s chromatin mark was also closely correlated to cell-type specific expression of putative gene targets of enhancers. It was also noted from a genome wide study that most potential regulatory elements were enriched only by the mono-methylated version of this histone 3.
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Citations
Measurement of lysine-specific demethylase-1 activity in the nuclear extracts by flow-injection based time-of-flight mass spectrometry.
J Clin Biochem Nutr . 2015 Feb 13 ; 56(2) 123 | DOI : 10.3164/jcbn.14-99
- C. Sakane
- et al