Peptides

KT2 - 1mg

221.00
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  • Cat.Number : AS-65672
  • Availability :
    In stock

Quantity

KT2 is a cationic amphipathic peptide modified from Crocodylus siamensis Leucrocin I. This peptide had been shown to inhibit HeLa cell viability1, 2, to induce apoptosis in HCT-116 cells both in vitro and in vivo 3-5 and to restrain HCT-116 cell migration4. The study also indicated that KT2 inhibits the migration and invasion of human melanoma cells by decreasing MMP-2 and MMP-9 expression through inhibition of FAK, uPA, MAPK, PI3K/AKT NF-kB, and RhoA–ROCK signaling pathways.

Specifications

Chemistry
Sequence one letter code
  • NGVQPKYKWWKWWKKWW-NH2
Sequence three letter code
  • H-Asn-Gly-Val-Gln-Pro-Lys-Tyr-Lys-Trp-Trp-Lys-Trp-Trp-Lys-Lys-Trp-Trp-NH2
Molecular Formula
  • C126H165N31O20
Molecular Mass/ Weight
  • 2432.28
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Crocodylus siamensis

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