Integrin-Binding Site, GRGDNP - 1 mg
- Cat.Number : AS-62049
- Manufacturer Ref. :
-
Availability :
In stock
This RGD-containing sequence is integrin-binding site. RGD peptides are found in both extracellular matrix (ECM) (e.g., collagen, osteopontin, fibronectin, and vitronectin) and non-ECM proteins (e.g., disintegrins). RGD-containing peptides are recognized by several integrins. This peptide targets both alphavbeta3 and alpha5beta1 integrins. Interaction of the RGDN sequence with endothelial alpha5beta1 integrin causes endothelin-mediated arteriolar vasoconstriction. This peptide influences the IkappaB kinase (IKK)/nuclear factor-kappaB (NF-kappaB) activation. It also controls the cardiac contractile function.
Specifications
Chemistry | |
Sequence one letter code |
|
---|---|
Sequence three letter code |
|
CAS registry number |
|
Molecular Formula |
|
Molecular Mass/ Weight |
|
Modification | |
Conjugation |
|
Quantity & Purity | |
Purity |
|
Storage & stability | |
Form |
|
Storage Conditions |
|
Activity | |
Biomarker Target | |
Research Area | |
Sub-category Research Area | |
Usage |
|
Source | |
Source / Species |
|
Codes | |
Code Nacres |
|
Downloads
You may also be interested in the following product(s)
![Tube of Collagen C-Telopeptide, human](/assets/cache/f521c9a2-ff1a-4c96-a32c-0db22ec5ed16/500x500/as-63837-img-en-as-63837-01.jpg)
![Tube of FN-A208 Fusion Peptide](/assets/cache/6559a0c2-7ef5-4a90-b816-208f1a324b03/500x500/as-65007-img-en-as-65007-01.jpg)
![Tube of Laminin Pentapeptide](/assets/cache/df9a039d-5e95-4804-aead-af6e30d94817/500x500/as-20806-img-en-as-20806-01.jpg)