Peptides
CDK5 Substrate [PKTPKKAKKL] - 1 mg
€127.00
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- Cat.Number : AS-60026-1
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The native peptide PKTPKKAKKL is derived from histone H1 peptide sequence that is docked in the active site of cyclin-dependent kinase 5. It is an effective CDK5 substrate (Km = 40 µM).
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Citations
S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by β-amyloid peptide
PNAS . 2011 Aug 23 ; 108(34) 14330 | DOI : https://doi.org/10.1073/pnas.1105172108
- J. Qu
- et al
Kinetic Mechanistic Studies of Cdk5/p25-Catalyzed H1P Phosphorylation: Metal Effect and Solvent Kinetic Isotope Effect
Biochemistry . 2010 Jun 15 ; 49(23) 4921 | DOI : 10.1021/bi100244j
- M. Liu
- et al