Caspase 1 (ICE) Substrate 3f, fluorogenic - 5 mg
- Cat.Number : AS-25285-5
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Caspase-1 substrate; AFC (7-amino-4-trifluoromethylcoumarin)-derived caspase substrates are widely used for the fluorimetric detection of various caspase activities. Cleavage of AFC peptides by caspases generate strongly fluorescent AFC that is monitored fluorimetrically at 500-510 nm with excitation of 370-390 nm.
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Citations
HMG-CoA reductase inhibitors activate caspase-1 in human monocytes depending on ATP release and P2X7 activation.
J Leukoc Biol . 2012 Nov 16 ; 93(2) 289 | DOI : 10.1189/jlb.0812409.
- Y.H. Liao
- et al