[Arg(Me2a)26]-Histone H3 (15-36)-GGK(Biotin) - 1 mg
- Cat.Number : AS-65261-1
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This peptide is histone H3 (15-36) asymmetrically dimethylated at Arg26, followed by a C-terminal GGK with biotinylation on the side chain of Lys. Dimethylation at Arg26 is catalyzed by CARM1 and inhibits deimination by peptidylarginine deiminase (PADI)-4. Arginine methylation of histone H3 is associated with transcriptional activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
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Citations
PELP1 oncogenic functions involve CARM1 regulation.
Carcinogenesis . 2013 Mar 13 ; 34(7) 1468 | DOI : 10.1093/carcin/bgt091
- M. Mann
- et al