Angiotensin I, human
- Cat.Number : AS-20627
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This human Angiotensin I (Ang I) sequence also corresponds to horse, sheep, pig, and rat Ang I. Ang I is cleaved to Ang II by the angiotensin-converting enzyme (ACE). There is also evidence for non-angiotensin-converting enzyme-dependent conversion of Ang I to Ang II. Human chymase efficiently converts the 10-mer Ang I to the 8-mer hormone Ang II by splitting the Phe8-His9 bond in Ang I.
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Citations
Rapid online nonenzymatic protein digestion combining microwave heating acid hydrolysis and electrochemical oxidation.
Anal Chem . 2010 Dec 07 ; 83(1) 359 | DOI : 10.1021/ac1024705
- F. Basile
- et al
The use of acetone as a substitute for acetonitrile in analysis of peptides by liquid chromatography/electrospray ionization mass spectrometry.
Rapid Comm Mass Spectrom . 2010 Jan 01 ; 24(1) 6 | DOI : 10.1002/rcm.4352
- T. Keppel
- et al
Characterization of 4-hydroxy-2-nonenal-modified peptides by liquid chromatography-tandem mass spectrometry using data-dependent acquisition: Neutral loss-driven MS3 versus neutral loss-driven electron capture dissociation.
Anal Chem . 2009 Jan 15 ; 81(2) 782 | DOI : 10.1021/ac802015m
- N. Rauniyar
- et al