5' Thiophosphate - 1 modification
- Cat.Number : MD-MF060-05004
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Thiophosphates (also known as phosphorothioates) are chemical compounds containing one or more sulfur and oxygen atoms linked to a phosphorus atom.
Monothiophosphates have a general chemical formula : [PO3S]3- and are used in oligonucleotides to increase the backbone resistance against nuclease digestion.
These analogs of phosphate with the substitution of a non-bridging oxygen by sulphur can be used in transcription studies, silencing…
Thiophosphates also known as Phosphorothioate bonds possess an increased resistance against nucleases due to the substitution of a non-bridging oxygen by sulphur.
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