390 MMP FRET Substrate XI - 5 mg
- Cat.Number : AS-27109
- Manufacturer Ref. :
-
Availability :
In stock
Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This substrate is readily hydrolyzed by MMP-8, 9 and collagenase-3 (MMP-13), Abs/Em = 325/393 nm. The hydrolysis is inhibited in a 1:1 stoichiometric fashion by the tissue inhibitors of metalloproteinases, TIMP-1, TIMP-2, and TIMP-3.
Specifications
| Chemistry | |
| Sequence one letter code |
|
|---|---|
| Sequence three letter code |
|
| Molecular Formula |
|
| Molecular Mass/ Weight |
|
| Properties | |
| Absorbance (nm) |
|
| Emission (nm) |
|
| Modification | |
| Conjugation type |
|
| Modification Name | |
| Conjugation |
|
| Quantity & Purity | |
| Purity |
|
| Storage & stability | |
| Form |
|
| Storage Conditions |
|
| Activity | |
| Application | |
| Biomarker Target | |
| Detection Method | |
| Research Area | |
| Sub-category Research Area | |
| Usage |
|
| Codes | |
| Code Nacres |
|
Downloads
You may also be interested in the following product(s)
